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hematology comparison dermatology fingernail lines monoclonal nail nails pathology agglutinin anemia ascites clinical cold disease eosinophilia eosinophilic erythematosus gammopathy hearing
Nail Findings & Associated Conditions Change in color, texture, or shape can be harmless, but may suggest
underlying systemic disease ... Onycholysis • Transverse ... fingernail #pathology #differential ... #diagnosis #dermatology ... #nails #table #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Nail Findings & Associated Conditions Change in color, texture, or shape can be harmless, but may suggest
underlying systemic disease ... Onycholysis • Transverse ... fingernail #pathology #differential ... #diagnosis #dermatology ... #nails #table #
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Schnitzler syndrome ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Hypereosinophilic Syndrome ... , wt loss; CV, CNS ... #pulmonary #differential ... #diagnosis #comparison ... #table #eosinophilia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... younger pts) Differential ... hemolytic #anemia #hematology ... #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... and CNS • Headache ... neuropathy • Transverse ... Erythematosus #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Hearing Loss - Differential ... Diagnosis Framework ... auditory nerve (CN ... II ○ Susac’s syndrome ... #Diagnosis #otology
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