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differential management vasculitis activation autoimmune behcet cauda caudaequina causes classification disease equina erythematosus hematology lupus macrophage mas myopathy myositis neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... and diplopia) • Vascular ... Oral aphthae : SLE ... • Arthritis: SLE ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... neuropathy • Transverse ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... erythematosus [SLE ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
(CES) is usually ... myelopathy • Transverse ... lumbar stenosis • Vascular ... • Provocative Tests ... absent anal wink test
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Diagnosis: • Dry ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... pulse deficits vascular ... chorioretinitis, CNS ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... and bullous or vesicular ... retinopathy Lab Tests ... vasculitis, and SLE ... #rheumatology #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... along with (VEGF) vascular ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... muscle disease/muscular ... Myositis #Myopathy #rheumatology
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