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diagnosis differential sle antinxp2dm classification dermatomyositis eularacr granulomatosis macrophage monoclonal oncology paraproteinemias polyangiitis polychondritis rash relapsing sapho vasculitis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... • Systemic lupus ... lupus erythematosus ... #Management #Hematology ... #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... vasculitis #Dermatologic ... #dermatology #rash ... #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic ... Lupus Erythematosus ... pericarditis • Hematologic ... #Lupus #Erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... lupus erythematosus ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Manifestations: ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Osteoarticular manifestations ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management ... #Dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... had more severe disease ... #diagnosis #management ... #rheumatology # ... dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... ischemia • Skin: Erythematous ... MPO > PR3 60/ GPA ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
manifestation) ... and fatigue Criteria ... chondritis • Ocular ... • Lymphoma • GPA ... Polychondritis #rheumatology
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