8 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... differential #diagnosis #AIDS
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
conjunction with symptoms ... nervous system (CNS ... diagnosis and treatment ... skull neoplasms (e.g ... MRI lesions and clinical
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... mononuclear cells in the CNS ... -> microglial activation ... • Depressive symptoms ... syndrome of HAD
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Clinical Presentation ... Fever is the main clinical ... nervous system (CNS ... Treatment: • Corticosteroids
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Neurological symptoms ... narrowing on MRA/CTA ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... be present: • AIDS ... initiation Clinical ... pleural effusions, CNS
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... involve PNS and CNS ... Induced Lupus: • Symptoms ... Chronic B-cell activation
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
to days after surgery ... starting amiodarone treatment ... respiratory distress syndrome ... gradually with symptoms ... LDH • ↑ ESR, CRP