20 results
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
autoimmune disorder ... at least: • 1 clinical ... to be present Treatment ... #diagnosis #management ... #anticoagulation
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
calculators - HAS-BLED (atrial ... validated for VTE treatment ... studies suggest net clinical ... bleeding risk • No RCTs ... #Factors #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... , Seizure disorders ... (for secondary APS ... cerebritis #diagnosis #management ... #treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
a gas exchange disorder ... shunt (Type 2) Clinical ... cycles after right atrial ... ) on room air Treatment ... #treatment #hepatology
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
Meta-analyses of RCTs ... Managing BPD Clinical ... with ‘treatment ... as usual’. ... UK national BPD clinical
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Clinical Manifestations ... limb or joint disorders ... #Diagnosis #Management ... #treatment #neurology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Change in clinical ... Anticoagulation ... upper abdominal/thoracic ... CARP, DECREASE V trials ... medical and surgical management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... Generalized fatigue - ALS ... Imaging - CT Chest ... Drugs, infection, surgery ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... immunophenotype Clinical ... Waiting" →several RCTs ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
• Classic triad ... leukocytosis, psychiatric disorders ... of anesthesia, surgery ... certain drugs (such as ... and then surgery