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management anticoagulant anticoagulants anticoagulation chemotherapy cyp3a4 inducers inhibitors interactions oncology oral perioperative pglycoprotein preop reversal vte
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table #DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... Table #DOAC ... VTE #Management #Pharmacology ... #Comparison #Table
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... surgery or urgent ... anticoagulant treatment ... not available #DOAC ... #Reversal #NOAC
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
determine timing of DOAC ... interruption per treatment ... table ... postoperative #DOAC ... #pharmacology #
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... content/133/4/291 #DOAC ... #Interactions #Table ... #Pharmacology
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