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Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
less than 200 cells ... Antimicrobial treatment ... more than 200 cells ... Generally >3 cm diameter ... opportunistic #InfectiousDiseases
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... in the CNS ○ ... The clinical syndrome ... Treatment: • HAART
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk: Diabetes ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
overgrowth of cells ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... mature plasma cells ... Hypoalbuminemia Treatment