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diagnosis differential hematology bruising algorithm classification cryofibrinogenemia cryoglobulinemia cryoglobulins hemostasis platelet thrombocytopenia types workup
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... • Steroids • Vasculitis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... (CVID, WAS), (neurologic ... (rituximab tx candidate ... #Workup #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Vascular Sludging ... classification #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of vascular integrity ... discern these causes ... Disruption in vascular ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract, and often causes ... Skin lesions (red macules ... pulmonary disease, and ocular ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... malignancies, vasculitis ... cryoglobulinemia Associated Disorders ... pulmonary emboli, and ocular ... cryoglobulins • Negative causes
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