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diagnosis differential management symptoms vasculitis autoimmune behcet classification disorders extraocular hematology immune inflammatory iris localization manifestations monoclonal movement myopathy myositis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular ... #symptoms #rheumatology
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
One-and-a-half Syndrome ... Skew Deviation Casey ... #Localization #ophthalmology ... #neurology #differential ... #diagnosis #ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... pain • Extra-CNS ... Manifestations #diagnosis #neurology ... #symptoms #signs
Ptosis - Differential Diagnosis Framework Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
disease affecting ... Myasthenia gravis • Ocular ... lens wearing • Ocular ... • Scarring • Ocular ... #ocular
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... , and ocular inflammation ... ulcers, cutaneous, ocular ... : Ocular inflammatory
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... Hypergammaglobulinemic macular ... Sneddon-Wilkinson disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... , and ocular inflammation ... ulcers, cutaneous, ocular ... : - Ocular inflammatory ... purpura: strong sign
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... #Rheumatology #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... skin lesions, ocular ... Zoster flare, ocular ... Parvovirus B19 • Candida
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused ... /muscular atrophy
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