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diagnosis fungal microbiology morphology pathology endocarditis infections infectiousdiseases bcnie clinical infective negative yeasts bacteria betadglucan biomarkers bloodculture cardiology causes cnie
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
Gram-negative bacilli - Fungi ... (Candida, Aspergillus ... Histoplasma) - Culture ... streptococci - Culture ... Pathogens #Diagnosis #Differential
Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues Yeasts with Pseudohyphae: •
Consistent with Candida ... spp. however Aspergillus ... other hyaline fungi ... #microbiology #differential ... septations #pathology #atlas
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... BCNIE #Causes #differential ... diagnosis #causes #culture
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues Broad-based budding yeasts: • Description: Broad-based
other hyaline fungi ... with dematiaceous fungi ... yeasts #fungal #fungi ... #microbiology #differential ... morphology #pathology #atlas
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... #fungus #comparison ... #table
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas # ... key #comparison
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues Broad-based budding yeasts: • Description: Broad-based
Coccidioides spp, Candida ... Cryptococcus, and Aspergillus ... pathology #clinical #atlas ... #fungi #microbiology ... #differential #
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... bacteria) and 18S ( fungi ... Endocarditis #diagnosis #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
component of many fungi ... • Pathogens: Candida ... BAL GM does not differentiate ... closely related fungi ... Galactomannan #diagnosis #comparison
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