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diagnosis differential infectiousdiseases cardiology infective negative bcnie fungal management microbiology table algorithm bacteria bloodculture bloodcultures causes clinical cnie fungi fungus
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
for Infective Endocarditis ... bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... streptococci - Culture
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
with Infective Endocarditis ... Negative Blood Cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... #Infective #Endocarditis
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... negative infective endocarditis ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #negative #Endocarditis
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas # ... key #comparison
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... staphylococci Culture ... Tropheryma Whipplei • Aspergillus ... • Blood cultures
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... Negative #Infective #Endocarditis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... Hypercoagulable (APLAS ... 90% of IE cases Culture ... Tropheryma Whipplei • Aspergillus ... #Endocarditis
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... fungi #fungus #comparison
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