My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior to cultures? -> Decreased yield due to antibiotic therapy - Number one cause of culture negative IE - Could they have a fastidious bacteria? Eg: C. burnetii , Bartonella, Brucella, Tropheryma -> Serological Testing - Could this be a non-bacterial pathogen? Fungal (Histoplasma/Aspergillus) / Mycobacterial etc. -> Serological Testing - Is the patient a surgical candidate? -> Serological Testing -> Histopathology Dr. Ahmed Babiker @Ahmed_HBabiker #Infective #Endocarditis #Negative #BloodCultures #Diagnosis #Management #Algorithm
