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fungal betadglucan biomarkers bloodcultures endocarditis fungi fungus infective management microbiology staining stains table
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Blood Cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis ... #Management #Algorithm
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Galactomannan Beta-D-Glucan ... • Pathogens: Candida ... Coccidioides - Negative ... Cryptococcus - Negative ... #diagnosis #comparison
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... • India ink - "Negative ... #microbiology #microscopy ... #staining #diagnosis
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