6 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
negative infective ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... , these bacteria ... #BCNIE #cardiology
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
bacilli - Fungi ... (Candida, Aspergillus ... bacilli - Fungi ... #Endocarditis #Bacteria ... #Pathogens #Diagnosis
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... remain negative ... or fungi (grows ... (Aspergillus, Candida ... PCR for specific pathogens
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
have a fastidious bacteria ... this be a non-bacterial ... pathogen? ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... • Coagulase-negative ... Tropheryma Whipplei • Aspergillus ... • Persistent bacteremia ... diagnosis #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS ... Negative: • Bartonella ... Tropheryma Whipplei • Aspergillus ... • Persistent bacteremia ... Differential #Diagnosis #cardiology