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diagnosis differential endocarditis infectiousdiseases cardiology causes algorithm bcnie comparison fungal management microbiology workup active activetb bacteria betadglucan biomarkers bloodculture bloodcultures
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
Responsible for Infective ... bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... negative #Infective
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
My Patient with Infective ... Blood Cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... Ahmed_HBabiker #Infective
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... negative infective ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #negative #Endocarditis
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... remain negative ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #BloodCulture #Negative
Causes of Dysuria - Differential Diagnosis Algorithm Pyuria - Leukocytes on Dipstick/Microscopy - Bacteriuria & Hematuria -
Leukocytes on Dipstick/Microscopy ... Urinary Tract Infection ... Urinary Tract Infection ... Hematuria - Dipstick negative ... Vaginitis • Candida
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
developing active infection ... • Tuberculosis infection ... TB AFB smear microscopy ... because false-negative ... Mycobacterial culture
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
• Pathogens: Candida ... , Aspergillus ... Coccidioides - Negative ... invasive fungal infection ... Cryptococcus - Negative
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... • Coagulase-negative ... Tropheryma Whipplei • Aspergillus ... • Blood cultures
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... • India ink - "Negative ... #microbiology #microscopy
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
) • Fungal - Aspergillus ... , Blastomyces, Candida ... Autoantigens - Infection-negative ... lymphocytic, infection-negative
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