13 results
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... Bacteria #Pathogens #Diagnosis ... #Differential #
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Blood Cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis ... #Management #Algorithm
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... BCNIE #Causes #differential ... #diagnosis #causes ... #culture #negative
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
result with no clinical ... AFB smear microscopy ... because false-negative ... Mycobacterial culture ... Mycobacterial culture
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... antimicrobials, clinical ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #differential #
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues
Broad-based budding yeasts:
 • Description: Broad-based
Cryptococcus, and Aspergillus ... yeasts #pathology #clinical ... #atlas #fungi # ... microbiology #differential ... #diagnosis
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Virus • Fungal: Candida ... Cryptococcus Neoformans, Aspergillus ... Renal #Transplant #differential ... #diagnosis #kidney ... #blood #urine #management
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
• Pathogens: Candida ... Coccidioides - Negative ... cut-offs defined in clinical ... BAL GM does not differentiate ... Galactomannan #diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... • Coagulase-negative ... Tropheryma Whipplei • Aspergillus ... Marantic (NTBE) Differential ... #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... Hypercoagulable (APLAS ... aureus, Coagulase-negative ... Negative: • Bartonella ... Tropheryma Whipplei • Aspergillus