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diagnosis endocarditis differential cardiology infective negative bcnie algorithm bacteria blastomycosis bloodculture bloodcultures causes cnie fungal incidence infections microbiology mycoses pathogens
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... streptococci - Culture ... #Differential #InfectiousDiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... diagnosis #causes #culture ... #Endocarditis #InfectiousDiseases
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Negative Blood Cultures ... antibiotics prior to cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis #Management
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... separate blood cultures ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... differential #workup #infectiousdiseases
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... Endocarditis #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS ... 90% of IE cases Culture ... staphylococci Culture ... Tropheryma Whipplei • Aspergillus ... Diagnosis #cardiology #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Confirmed by culture ... ASPERGILLOSIS • Aspergillus ... Diagnosis: • Culture ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
Blastomycosis Summary Pathogen: • Dimorphic fungus - Blastomyces dermatitidis or Blastomyces gilchristii. • The fungus lives
in New York and Canada ... Skin tissue 2) Culture ... Blastomycosis #diagnosis #management ... #treatment #infectiousdiseases
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