8 results
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Negative Blood Cultures ... antibiotics prior to cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis #Management
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... diagnosis #causes #culture ... #CNIE #BCNIE #cardiology
Common Fungal Pathology 
 • Candida - Small yeast intermingled with pseudohyphae
 • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas #
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... Endocarditis #diagnosis #management ... #cardiology
Natural history
Aneurysms may progress in size as a result of gradual wall weakening [6], with rupture
cm in men [7] (Table ... Table 1: Annual ... rupture risk according ... References: Radiology ... 37:1106-1117 #Management
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... fungus #comparison #table
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS ... 90% of IE cases Culture ... staphylococci Culture ... Tropheryma Whipplei • Aspergillus ... Differential #Diagnosis #cardiology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Management during ... Management during ... Delivery • Stable ... • During a future ... #cardiology #treatment