7 results
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... this be a non-bacterial ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis #Management
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
for Infective Endocarditis ... bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... #Bacteria #Pathogens
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
negative infective endocarditis ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... under BCNIE, these bacteria ... #negative #Endocarditis
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... Negative #Infective #Endocarditis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... • Persistent bacteremia ... #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Endocarditis - Overview ... Hypercoagulable (APLAS ... Tropheryma Whipplei • Aspergillus ... • Persistent bacteremia ... #Endocarditis
Suspected catheter-related bloodstream infection - Management Algorithm
 • Temperature 37.8 C   • Rigors
Obtain blood cultures ... Hemodynamically stable ... Persistent fever and/or bacteremia ... metastatic infection (endocarditis ... Persistent fever and/or bacteremia