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diagnosis algorithm comparison endocarditis fungal treatment aviumcomplex blastomycosis bloodcultures bloodstream cardiology catheter clinical crbsi fungi fungus hivaids idsa infection infections
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Negative Blood Cultures ... antibiotics prior to cultures ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate ... BloodCultures #Diagnosis #Management
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas #
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... #staining #diagnosis ... fungus #comparison #table
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
Obtain blood cultures ... Hemodynamically stable ... 72 hours after starting ... 72 hours after starting ... Hernodynamically stable
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... Endocarditis #diagnosis #management
Blastomycosis Summary Pathogen: • Dimorphic fungus - Blastomyces dermatitidis or Blastomyces gilchristii. • The fungus lives
in New York and Canada ... swelling or a chronic draining ... Skin tissue 2) Culture ... Blastomycosis #diagnosis #management
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS Preventing 1st Episode of Disseminated
mycobacterial blood culture ... please refer to Table ... ruled out before starting ... Prevention #Treatment #management
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