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Pathophysiology and Effects of Insulin Deficiency #Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Ketoacidosis (DKA ... HHS) Absolute Insulin ... Type I DM: No insulin ... stresses that ↑ insulin ... Polydipsia #dka
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
and Euglycemic DKA ... for euglycemic DKA ... • Increased insulin ... and surgery) • Insulin ... SGLT2 #Euglycemic #DKA
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity #DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... Continue insulin ... and subcutaneous insulin ... #DKA #EDKA #Insulin
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS = insulin ... restart any home insulin ... look like overlap DKA
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA) DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... Insulin is the primary ... the absence of insulin ... In DKA, the normal
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... ketoacidosis (DKA ... caused by complete insulin ... • Euglycemic DKA ... HHS) - partial insulin
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... along with IV insulin ... Treating DKA: 1) ... +++ fluids. 2) Insulin
Events Resulting from Acute Insulin Deficiency in Type 1 Diabetes Mellitus If left untreated, insulin deficiency may
Resulting from Acute Insulin ... left untreated, insulin ... #DKA #Ketoacidosis ... Pathophysiology #Insulin
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