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diagnosis differentiation leukostasis lysis oncology tumor
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... common • Imaging: CXR ... #APML #diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... leukapheresis - TLS ... #TLS #diagnosis ... #management #hematology
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