8 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Yellow Nail Syndrome ... • Central Nail Canal ... Nail #fingernail #pathology ... differential #diagnosis #dermatology ... #nails #table #
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Yellow Nail Syndrome ... • Central Nail Canal ... Nail #fingernail #pathology ... differential #diagnosis #dermatology ... #nails #table #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... and increased B-cell ... renal failure Clinical ... Self-limiting, chronic but stable ... Diagnosis #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... Low or absent NK cell ... management #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... variants of both • Acral ... Schistocytes, helmet cells ... treatment #management #hematology