3 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... excess: - ... expansion (e.g. carpal ... endocrinology #pathophysiology ... #pituitary
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... overgrowth: • Carpal ... #GH #Excess #Overproduction ... #diagnosis #signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... excess occurs before ... malignancy Pathophysiology ... islet cell tumor, excess ... Endocrinology #Treatment #Pathophysiology