18 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... #Features #Signs ... #Symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Cardiovascular disease ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
• Salt wasting crisis ... "salt wasting crisis ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... small joints (wrists ... boggy" joints, esp carpal ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
intervertebral canal ... Restrictive Pulmonary Disease ... #Scoliosis #pathophysiology ... msk #diagnosis #signs ... #symptoms
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Myasthenic Crisis ... X-ray and lung ultrasound ... or TSH level if symptoms ... monitoring (vital signs ... #Myasthenic #Crisis
Clinical features of Liver Disease in Children

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings #Diagnosis #Peds #Pediatrics #Hepatology

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features of Liver Disease ... #LiverFailure #Signs ... #Symptoms #PhysicalExam ... Diagnosis #Peds #Pediatrics ... #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... but elevated as disease ... diagnosis #workup #hepatology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... remainder likely arises ... /Symptoms/Findings ... Agammaglobulinemia #XLinked #pathophysiology