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diagnosis pathophysiology gh growthhormone 21hydroxylasedeficiency 21ohd central diabetes excess features feedbackloop findings genetics hyperparathyroidism hyperthyroid hyperthyroidism hypothyroidism insipidus myopathy neurology
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
and signs. ... Symptoms: Tiredness ... peripheries, Carpal ... reflexes, Anaemia #Hypothyroid ... #PhysicalExam #Endocrinology
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
ADH (SIADH) - Comparison ... Insipidus #SIADH #Comparison ... Pathophysiology #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... and Signs Hypothyroidism ... #Hyperthyroid # ... Symptoms #Signs ... #Diagnosis #endocrinology
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... Rhabdomyolysis (rare) #Hypothyroid ... pathophysiology #signs ... #symptoms #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Tertiary Lab Comparison ... Phosphate Physical Symptoms ... : Commonly no signs ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Characteristics of Peripheral and Central Vertigo PERIPHERAL VERTIGO • Onset: Sudden • Intensity: Severe initially, often decreasing
classic posterior canal ... in horizontal canal ... diagnosis #findings #signs ... #symptoms #comparison
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology ... #peds #pediatrics
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