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diagnosis pathophysiology growthhormone symptoms acromegaly excess feedbackloop management overproduction pituitary ra rheumatoid rheumatology treatment
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... expansion (e.g. carpal ... tunnel, OSA, Incr ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... overgrowth: • Carpal ... Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Rheumatoid Arthritis ... Involvement, Spares DIP, Carpal ... Tunnel, Sicca Syndrome ... #Rheumatoid #Arthritis ... #rheumatology #signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... tunnel) and OSA ... decade → peripheral/acral ... Beckwith Wiedemann syndrome ... Diagnosis #Management #Endocrinology
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