16 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
syndrome (Clinical ... Skin lesions • Positive ... disease) Differential ... Syndrome #diagnosis #management ... #rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... • Ocular: uveitis ... #diagnosis #management ... #treatment #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... initiation Clinical ... skin lesions, ocular ... Zoster flare, ocular ... #Diagnosis #Management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... likely it will be clinically ... ANA #patterns #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... Evolution: Chronic disease ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... VASCULITIS: • Behçet ... Differential ... Presentation - Systemic Symptoms ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... (Cold-induced symptoms ... dehydrogenase • Positive ... younger pts) Differential ... hemolytic #anemia #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... • IRIS might ... should be based on clinical ... Demyelinating disease ... and <25% culture positive
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... • Progressive symptoms ... vasculitis • Behcet ... #Diagnosis #Rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Dermatomyositis Clinical ... Myoglobinuria: UA positive ... of underlying disease