30 results
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... with severe symptoms ... #Inflammatory #Syndrome
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Early Latent: • Positive ... testing • No symptoms ... first year of infection ... • Gummatous • Nodular ... Late Latent: • Positive
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Iris 7. ... Ocular Adverse Effects ... Trauma Cornea/Iris ... Uveitis Lens: • Cataracts ... • Sjögren’s syndrome
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... Brushfield spots in iris ... susceptibility to infections ... impairment from cataracts ... #Downs #Syndrome
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
IRIS might ... CD4 Variable • Symptoms ... disorders • Symptoms ... and <25% culture positive ... patients with IRIS
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Dacryoadenitis: infection ... are no longer infectious ... normal: - extra-ocular ... movements and globe position ... diagnosis #signs #symptoms
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... - Due to Viral infection ... (Cold-induced symptoms ... dehydrogenase • Positive ... rewarming • Symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... complications (AQP4-positive ... erythematosus, Sjögren syndrome ... diagnosis #neurology #symptoms
Headache Syndromes 
Sudden onset of pain - "Thunder clap" with any decreased mentation, any positive focal
Headache Syndromes ... mentation, any positive ... with stroke-like symptoms ... pressure or dental infection ... #diagnosis #symptoms
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... previous neurologic symptoms ... and not direct infection ... meningeal enhancement, infarctions