10 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
M > F Clinical Manifestations ... skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... Skin lesions • Positive ... management #signs #symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... desaturation, Scotoma, Ocular ... complications (AQP4-positive ... #diagnosis #neurology ... #symptoms #signs
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary and renal manifestations ... : - ANCA-positive ... erythematosus, Rheumatoid arthritis ... allopurinol), Infection ... DAH, rule out infection
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Neurological Manifestations ... Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... and not direct infection ... differential #TB #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical manifestations ... skin lesions, ocular ... Zoster flare, ocular ... #Inflammatory #Syndrome
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Ocular syphilis ... manifestations ... exposure to or symptoms ... serology but do ... aneurysm and coronary arteritis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
to exclude are infections ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Manifestations depend ... vasculitis vs infection ... Biopsies remain positive ... Temporal #Signs #Symptoms
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Malignancy • Infections ... pulmonary emboli, and ocular ... to medium-sized arteries ... Antiphospholipid syndrome
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
by culture or serology ... osteoarticular, pulmonary, ocular ... Diagnosis: • Serology ... Meningitis, septic arthritis ... have positive blood