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C. Difficile Infection in IBD - IBD Algorithm

Background
Complications
CDI Testing Algorithm
CDI Recurrence

Dr. Wade Billings @wabillin

#Clostridioides #difficile #CDiff
Difficile Infection ... Complications CDI ... CDI Recurrence ... Clostridioides #difficile ... #CDiff #CDifficile
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection ... (CDI) - Diagnosis ... IDSA 2021 CDI ... /ciab549 #CDI ... #Cdiff #Clostridioides
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Penicillium marneffei Parasitic ... : • CD4 < 200 ... in particular) Evaluation ... /diff, Blood and ... workup #diagnosis #evaluation
Guidelines on Management of Clostridioides difficile Infection (CDI) in Adults
 • Non-Severe CDI
 • Severe CDI
Infection (CDI) ... • Non-Severe CDI ... • Severe CDI ... • Fulminant CDI ... #CDiff #CDI #management
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS
Preventing Bacterial Enteric Illness:
 • Antimicrobial
IDSA Recommendations ... Bacterial Enteric Infections ... Treating Clostridium difficile ... Infection (CDI) ... Enteric #Bacterial #IDSA
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
Algorithm for the ... Evaluation of Acute ... C difficile assay ... Ova and parasite ... HIV infection or
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... →Activation of CD8 ... salmonella, ...), Parasites ... Still disease, Infection ... inhibitors under evaluation
Ulcerative Proctitis
Proctitis:
 • Affects 1/3 patients
 • Predictors of extension:
     - Disease
Infection (CMV, ... c-Diff, GCCT (LGV ... rectal prolapse, CD ... diagnosis #management #algorithm