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diagnosis management antidrugantibodies antitnffailure checkpointinhibitor colitis druglevels hematology im immune oncology plasmacytoma resistance solitary workup
Algorithm for managing the failure of anti-TNF therapy. ADA=anti-drug antibody; IM=immunomodulator; MOA=mechanism of action; TNF=tumor necrosis
Algorithm for managing ... failure of anti-TNF therapy ... factor #Management #GI ... #IM #IBD #AntiTNFFailure ... #BMJ
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
indicated Diagnostic Evaluation ... -4 • Consult GI ... Diff, Stool cx, ... diagnosis #management #algorithm ... #IBD
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... Less common - GI ... Diagnostic Evaluation ... • CBC + diff • ... • Radiation therapy
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