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diagnosis clinical differential management dermatology algorithm photo rheumatology causes hepatology pathophysiology physicalexam video treatment ucsdh pharmacology skinrash pocus radiology comparison
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Hepatomegaly • Skin ... disease • B cell ... and other C Cell ... workup #oncology #hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... : • Squamous cell ... • Bleomycin Hematologic ... : • Sickle Cell ... ulcerative #skinrash #dermatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
nose chondritis, skin ... vasculitis • Hematologic ... criteria for 1) hematologic ... (12%) • giant cell ... blood myeloid cells
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
of ALL is of B-cell ... lymphadenopathy • Blast cells ... involvement • T-cell ... -> Invade Skin: ... #Leukemia #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... symptoms (eg, skin ... Differential #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... low red blood cell ... just beneath the skin ... hematopoiesis cell ... Syndromes #diagnosis #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Anemia #oncology #hematology
Skin Cancer Overview - Basal Cell, Squamous Cell and Melanoma #Skin #Cancer #Basal #Squamous #Melanoma #Dermatology #Diagnosis
Skin Cancer Overview ... - Basal Cell, Squamous ... Cell and Melanoma ... #Skin #Cancer ... Squamous #Melanoma #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Malignancy (e.g. hematologic ... Angioimmunoblastic T-cell ... Seizures • Strokes Skin ... : • Chronic B-cell
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