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management differential hematology neurology pediatrics hemophagocytic hepatology hepatopulmonary hlh immune incomplete inflammatory iris lymphohistiocytosis macrophage mas ms multiple myelitis reconstitution
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... #Kawasaki #Disease ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Disease 1. ... other suggestive features ... echo is positive, treatment ... clinical and lab signs ... #Diagnosis #Peds
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... age, however the disease ... : HLH signs and ... symptoms can mimic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus • Kawasaki ... Histopathologic features ... Histopathologic criteria ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Signs and symptoms ... criteria for MS ... 85% of pts) → Enter
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Criteria: • Underlying ... with or without cirrhosis ... resolution of HPS features ... resolution of symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... criteria, but the ... onset of illness features ... progression of cirrhosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Alterations: - Sensory features ... Criteria: • Sensory ... • Bilateral signs ... and/or symptoms
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