12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Chronic leukemia ... - infiltrates (anemia ... smear: Blasts ... #Hematology #Oncology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... with extensive rouleaux ... #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cytometry • Peripheral ... smear: Smudge cells ... • Neutropenia, anemia ... leukemia #CLL
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell ... Analysis #hematology ... interpretation #clinical
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Diagnosis: • Peripheral ... smear → small rnature-appearing ... immunophenotype Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... non-specific red cell ... smear changes are ... #Hematology #Pathology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... and started on all-trans ... treatment, her peripheral ... blood smear showed ... #Clinical #Path
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Smear: • Dysplastic ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Leukemia • Idiopathic ... blood smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... thalassemia, and leukemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... approximately 5-10% of peripheral ... Tissue damage • Leukemia ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology