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diagnosis oncology leukemia workup algorithm anemia basophilia causes hemeonc hemolytic management mds myelodysplasia myelodysplastic syndromes testing tryptase
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... released during an allergic ... Myeloproliferative Disorders ... : • Chronic myeloid ... Diagnosis #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... eosinophilia, basophilia ... or functional neutropenia ... (Chronic Lymphocytic ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Cytopenias: • Neutropenia ... #Chronic #Lymphocytic ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... PRCA, autoimmune neutropenia ... #Chronic #Lymphocytic ... Leukemia #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
thalassemia, S Lepore • Basophilic ... Agglutination - Cold agglutinins ... inclusions - If infection ... Consider RBC membrane disorder ... Algorithm #workup #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Eosinophilic GI Disorders ... • Parasitic infections ... Causes: • Mast cell ... #Diagnosis #hematology ... #allergy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Syndromes #diagnosis #hematology
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