10 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... biliary obstruction, HELLP ... #Injury #Differential ... #Diagnosis #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... : Thrombotic thrombocytopenic ... Extravascular #Causes #differential ... #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... features: Hemolysis, Thrombocytopenia ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Diagnosis • ... • Congenital: HELLP ... Trauma: Shock liver ... Metabolic: Wilson Disease ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Infections: Hepatitis ... NAFLD, Autoimmune, HELLP ... , Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Pregnancy - AFLP, HELLP ... • Cholestatic disease ... • Alcoholic hepatitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... Diagnosis: Viral ... Hepatitis, Preeclampsia ... , HELLP, Intrahepatic ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Pregnancy: HELLP ... #differential # ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... hypersplenism and related thrombocytopenia ... Cirrhosis/acute hepatitis ... #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... and hepatitis ... specifically immune thrombocytopenia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management