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causes management nonpalpable rash activation algorithm coagulation dermatologic dic disseminated extravascular gpa granulomatosis hemolysis hemolytic macrophage mas palpable petechiae polyangiitis
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Petechial/Purpuric ... algorithmic approach can help ... , subcutaneous hemorrhages ... , disseminated intravascular ... #Diagnosis #Dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... red to purple, hemorrhagic ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
rash (6.7%) • Hemorrhagic ... reticularis Differential ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Manifestations of DIC: • Petechiae ... Acral cyanosis • Hemorrhagic ... #Coagulation #diagnosis ... treatment #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... in most cases; hemorrhage ... reflection of intravascular ... #Workup #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
dysfunction • Hemorrhagic ... with leukopenia, anemia ... , and thrombocytopenia ... #Management #Hematology ... #Rheumatology
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