6 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
algorithmic approach can help ... , subcutaneous hemorrhages ... , disseminated intravascular ... coagulopathy (DIC), or TTP ... #Diagnosis #Dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... red to purple, hemorrhagic ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... Manifestations of DIC: • Petechiae ... Acral cyanosis • Hemorrhagic ... #Coagulation #diagnosis ... treatment #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... in most cases; hemorrhage ... reflection of intravascular ... #Workup #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... , and thrombocytopenia ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology