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diagnosis hyperkalemia oncology potassium syndrome anthracycline apml cardiology differentiation encephalopathy hematology her2 neurology posterior pres reversible toxicity
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
controlled DM • Chemotherapy ... transfusion • HTN and edema ... reactions Common Drugs ... #diagnosis #causes ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
controlled DM • Chemotherapy ... transfusion • HTN and edema ... reactions Common Drugs ... #diagnosis #causes ... #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
disease, Cancer chemotherapy ... Etiology: • Pathophysiology ... Reversible course Differential ... abnormality, Medication/Drug ... Syndrome #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Attempt if high ... myalgias, HoTN, edema ... initiation • Differential ... sepsis), PE, DAH, CHF
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... Anthracyclines cause ... hypertension, peripheral edema ... cardiology #oncology #pharmacology ... #toxicity #chemotherapy
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