9 results
management cppd hematology blood disease product pseudogout reactions signs symptoms chondrocalcinosis comparison crisis deposition gout hemophagocytic hlh leukostasis lymphohistiocytosis lysis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... treatment (no calcium ... Syndrome #TLS #diagnosis ... #management #hematology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
> Clearance of calcium ... mineralization of calcium ... joint (sudden onset ... Signs #Symptoms #Pathophysiology ... #Diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... precipitates with calcium ... characterized by sudden onset ... • Nocturnal onset ... Gout #Comparison #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... SLE+++, Adult-onset ... Lymphohistiocytosis #diagnosis ... treatment #summary #rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... 4) Average age onset ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... at the time of diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
resembles ARDS, onset ... binds to serum calcium ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
resembles ARDS, onset ... binds to serum calcium ... #Transfusions #diagnosis ... #management #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... characterized by sudden onset ... culture used to diagnose ... Deposition #Disease #Rheumatology ... #diagnosis #management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
injury 2) Abrupt onset ... anemia (MAHA) Pathophysiology ... Biopsy to confirm diagnosis ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
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