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diagnosis management cppd disease hematology pseudogout signs chondrocalcinosis comparison deposition gout hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis polychondritis pyrophosphate relapsing
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
4) Average age onset ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... Features: • Many symptoms ... patients have no symptoms
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
> Clearance of calcium ... mineralization of calcium ... joint (sudden onset ... Disease #Signs #Symptoms ... #Pathophysiology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... precipitates with calcium ... characterized by sudden onset ... • Nocturnal onset ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary - Calcium ... Disease (CPPD) Pathophysiology ... precipitates with calcium ... characterized by sudden onset ... Deposition #Disease #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... : • Sudden onset ... + Nonspecific symptoms ... dysfunction DDX: • Sarcoidosis ... Polychondritis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
- Onset: Usually ... Common Signs and Symptoms ... Pathophysiology ... Diagnosis #Management #Hematology
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