1495 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium chloride ... thiazide-sensitive sodium chloride ... alkalosis • Normal or low ... • Congenital chloride
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... suction, Congenital chloride ... - Normal/low ... Bartter syndrome, Gitelman ... causes #urinary #chloride
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Alkalosis - Urinary Chloride ... alkalosis • Normal/low ... Bartter syndrome, Gitelman ... use The urine chloride ... Urine chloride is
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... - Bartter - Gitelman ... • Fatigue Chloride ... Pathophysiology #Nephrology #Chloride
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome • Urine Chloride ... krithicism #Gitelman
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Algorithm Urine chloride ... < 20 mmol/l - Chloride ... responsive (Chloride ... > 20 mmol/l - Chloride ... Bartter's Syndrome, Gitelman's
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman ... thiazide-sensitive sodium-chloride ... dr_missyhanna #Gitelman
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Normal Acid-Base: Low ... Ureterosigmoidoscopy • HTN, Low ... Bartter syndrome, Gitelman ... causes #potassium #low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
hyperaldosteronism • Low ... , NGT suction, Low ... Bartter Syndrome, Gitelman ... Renin-secreting tumor • Low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low ... , NGT suction, Low ... Bartter Syndrome, Gitelman ... Renin-secreting tumor • Low