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Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
• Hereditary Cholestatic ... of intrahepatic cholestasis ... hepatitis, hepatic cirrhosis ... ) Intrahepatic cholestasis ... drugs, biliary cirrhosis
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Primary Biliary Cirrhosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
def, Wilson's, Cholestatic ... dz Cholestatic ... Congenital, Others, Cirrhosis
Coagulation management in the bleeding cirrhotic #Management #INR #Coagulopathy #Cirrhosis #Cirrhotic #TEG #Transfusions
in the bleeding cirrhotic ... #Coagulopathy #Cirrhosis ... #Cirrhotic #TEG
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Hepatocellular and Cholestatic ... Hepatocellular or Cholestatic ... R ≤ 2 = Cholestatic ... Hepatocellular #Cholestatic
Pathogenesis of Cirrhotic Ascites #ascites #pathophysiology #hepatology #cirrhosis
Pathogenesis of Cirrhotic ... pathophysiology #hepatology #cirrhosis
Management of critically-ill cirrhotic patients Open Access Source (Intensive Care Med (2018) 44:1932–1935): https://link.springer.com/epdf/10.1007/s00134-018-5078-z?shared_access_token=rKBIIjC6Htq14G82yghJnfe4RwlQNchNByi7wbcMAY63FIMr4IeFUPHZTUFKckgGIQeEsXu7k1NhPo-T8ItytjuWlMH7y0kI6IydY2i7VzU4Y93MfuEKQruo-qIKnVF91JyuQsQbJNPJv3UJYPzkySdSktYPmFVd6xw1xJDLPqY%3D #cirrhotic #cirrhosis #Management #CriticalCare
critically-ill cirrhotic ... rKBIIjC6Htq14G82yghJnfe4RwlQNchNByi7wbcMAY63FIMr4IeFUPHZTUFKckgGIQeEsXu7k1NhPo-T8ItytjuWlMH7y0kI6IydY2i7VzU4Y93MfuEKQruo-qIKnVF91JyuQsQbJNPJv3UJYPzkySdSktYPmFVd6xw1xJDLPqY%3D #cirrhotic ... #cirrhosis #Management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... bile ducts causes cholestasis ... → Cirrhosis/Liver ... , Intrahepatic cholestasis ... , Drug-induced cholestasis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
RNA • R < 2: Cholestasis ... Obstruction: Cholestasis ... epithelia - Cholestasis ... ALT: typical of cholestatic ... hepatitis: < 1 • Cirrhosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
poisoning, ETOH Cholestatic ... elevation Labs in Cholestatic ... epithelia: - Cholestasis ... ALT: typical of cholestatic ... hepatitis: < 1 • Cirrhosis
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