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diagnosis hepatology dermatology injury pruritus secondary systemic drug gastroenterology hepatitis idiosyncratic induced liverenzymes primary
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... • Cholestatic ... Idiosyncratic #differential ... gastroenterology #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... Autoimmune hepatitis, PBC ... #diagnosis #algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Algorithm - Systemic ... and Primary Causes ... Tests/Enzymes: • Cholestatic ... #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Others • Cholestatic ... • Others #LFTs ... #Causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Tests/Enzymes: • Cholestatic ... renal failure/uremia ... Hyperthyroidism CBC ... secondary #systemic #generalized ... #causes
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