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diagnosis hepatology dermatology injury neurology pruritus secondary systemic abnormal acute alkaline alp dili elevated elevatedmcv elevation gastroenterology gravis hematology idiosyncratic
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Ducts - PBC ... Burak @kwburak #LFTs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Algorithm - Systemic ... and Primary Causes ... Tests/Enzymes: • Cholestatic ... #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Others • Cholestatic ... • Others #LFTs ... #Causes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Recreational Drugs ... Malignancy, 1° PBC ... #Acute #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... Intestine - Other causes ... biliary Cholangitis (PBC
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Mixed DILI • Cholestatic ... Idiosyncratic #differential ... gastroenterology #algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Tests/Enzymes: • Cholestatic ... renal failure/uremia ... Hyperthyroidism CBC ... secondary #systemic #generalized ... #causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Blood Smear • Drugs ... Neutrophils - Low RBC
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... - Differential ... Simple, Complex • Generalized ... , Recreational drugs ... , Liver failure,
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... nerve pathology - Generalized ... Miller Fischer and PCB ... precipitated by: Drugs ... Gravis #diagnosis #management
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