15 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... - Cholestatic Pattern ... Hepatocellular Pattern #LFTs ... #diagnosis #differential ... #algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... • Cholestatic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Autoimmune hepatitis, PBC ... melanoma, myeloma • Pregnancy ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... AIH, Wilsons, Pregnancy ... Ducts - PBC ... Burak @kwburak #LFTs
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... - Drugs - Pregnancy ... Primary biliary Cholangitis ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... titres, ↑ IgG • Cholestatic ... Primary biliary cholangitis ... Injury #Diagnosis #Algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... • Others • Cholestatic ... • Others #LFTs ... #Hepatology #LiverEnzymes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
→ Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... of pregnancy, Cardiac ... #workup #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Malignancy, 1° PBC ... Toxic: Medication, Pregnancy ... Causes #Acute #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Unconjugated Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #