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algorithm obstetrics pregnancy biliary cholangitis comparison disease fatty gap globulin hypertension icp injury lfts liverenzymes management obgyn pathophysiology pbc portal
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... , HELLP Moderate ... Others #LFTs #Hepatology ... #Causes
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... Clues to non-cirrhotic ... /acute hepatitis ... #Diagnosis #causes ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... infiltration) Differential ... Hepatitis, Preeclampsia ... , HELLP, Intrahepatic ... Pregnancy #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... - Cirrhosis ... - Alcoholic hepatitis ... #Causes #diagnosis ... hepatology #SAAG
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Syndrome (Hemolysis ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Vascular Causes ... • Pregnancy: HELLP ... : < 1 • Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... /Liver failure ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... disease: Cirrhosis ... gastric tumors • Hematology ... #diagnosis #hematology
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