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hepatology algorithm ascites injury acute chemistry druginduced gap globulin hepatomegaly hiv hypertension interpretation liverenzymes management pbc protein proteingap retroviral rheumatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... • Budd-Chiari Syndrome ... • Primary Biliary ... Cirrhosis #Hepatomegaly ... #Causes #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ... biliary cholangitis ... #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... biliary cholangitis ... #Hepatology #causes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary ... biliary cirrhosis ... #Differential # ... Hepatology #Cirrhosis ... #Causes
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 Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... Clues to non-cirrhotic ... /acute hepatitis ... biliary cirrhosis ... #Diagnosis #causes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... Viral hepatitis, ... #Biliary #Cirrhosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... : < 1 • Cirrhosis ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Duct Stone • Biliary ... • Others #LFTs ... #Causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
INR > 1.5 • Encephalopathy ... : < 1 • Cirrhosis ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... carcinomatosis - Primary ... #diagnosis #differential
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