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algorithm aflp management pregnancy albumin biliary chemistry cholangitis comparison fatty gap globulin gradient grading hellp hepatic hepatomegaly hepatopulmonary hps hypertension
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Cirrhosis ... #Causes #diagnosis ... hepatology #SAAG
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
(SAAG>I.I), esophageal ... Clues to non-cirrhotic ... /acute hepatitis ... #Diagnosis #causes ... #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... liver disease ( ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... Diagnosis #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Differential ... Diagnosis High albumin ... - Alcoholic hepatitis ... #Diagnosis #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Nonalcoholic fatty liver ... (Budd-Chiari syndrome ... #Differential # ... Hepatology #Cirrhosis ... #Causes
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... #Hepatology #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... hypoglycemia, encephalopathy ... Hepatitis, Preeclampsia ... #Pregnancy #hepatology ... #obstetrics #obgyn
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
INR > 1.5 • Encephalopathy ... : < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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